
Action is in our genes
We make precision therapies that make genomic testing actionable for every patient.

Founder’s Letter | Q4 2021
Dear Cancer,
As we enter into the closing quarter of an eventful year, I’d like to take this opportunity to share a recent reminder of why we began this journey. Elevation Oncology was founded not only to bring new targeted therapies to patients with cancer, but to shine a spotlight on the journey that we as a cross-disciplinary industry are taking to bring about a future where every patient can receive care built around understanding and targeting their unique tumor drivers. This involves asking ourselves some tough questions about the status quo, and what change each of us is in the position to enable.
The passionate team of patient advocates at OffScrip Media recently spoke with Elevation Oncology clinical investigator Dr. Stephen Liu about some of these tough questions in a new sponsored episode of their podcast series OUT OF PATIENTS entitled “Dear Cancer,”. Dr. Liu is an oncologist at Georgetown Lombardi Comprehensive Cancer Center who has dedicated his career to advancing the treatment of thoracic malignancies including NSCLC, an area of practice that has been truly transformed by precision medicine. He is interviewed by Matthew Zachary, a brain cancer survivor who has channeled his personal experiences into the creation of OffScrip Media, the first audio broadcast network and educational publisher focused on health equity and patient advocacy.
Bringing together the perspectives of patient, patient advocate, health care provider, and drug developer, Matt and Dr. Liu have a truly insightful discussion about the modern challenges facing patients with cancer and their treating physicians today, including:
- What does the 21st century “Patient Bill of Rights” look like, and should biomarker testing for cancer now be a right?
- Who is responsible for initiating the conversation about genomic testing and personalized treatment opportunities – the patient, or the physician?
- Given the rapidly changing landscape of approved and investigational treatment opportunities in oncology, it’s hard for any treating physician to keep up – is it ok for patients to ask for another medical opinion from a specialist?
We invite you to listen in on this conversation on your favorite podcast platform, or in the embedded player below. Furthermore, we invite you to join the conversation, and to help us build forward an industry that advocates for delivering more consistent and equitable care to patients in need. We look forward to working with you.


It takes a team to reach the summit
We are experienced oncology drug developers united by a shared passion for identifying true precision therapies that will illuminate a clear treatment pathway for our patients.
Join Our TeamLeadership
Shawn M. Leland is the Founder and Chief Executive Officer of Elevation Oncology overseeing all day-to-day operations. Shawn brings over a decade of experience in medical affairs and business development for the pharmaceutical/biotech industry, with a focus on building collaborations to realize the full potential of targeted and personalized therapeutics. Shawn has been involved in global transactions totaling more than $450 million in upfront payments and milestone payments at Eli Lilly, ARIAD Pharmaceuticals, Argos Therapeutics and Verastem Oncology. Shawn has also served as an expert strategic consultant for Catenion providing guidance on portfolio management for pharmaceutical/biotech companies.
Shawn resides in Denver, Colorado and enjoys snowboarding, hiking and cycling.

David Dornan brings to Elevation over two decades of industry and academic oncology drug discovery and development experience. His research spans across multiple therapeutic modalities targeting cancer susceptibilities and modulating the immune system to translate into meaningful therapeutic interventions for patients. He joins Elevation Oncology from Bolt Biotherapeutics. As Chief Scientific Officer, he was responsible for the scientific strategy and building of the company’s portfolio in targeted immunotherapies. Prior to this, David was the head of Oncology Research at Gilead, identifying, validating, and translating oncogenic targets into actionable entities with biologic and small molecule therapeutics and oversaw the integrated oncology strategy team. He began his career at Genentech, where he spent 10 years serving in positions of increasing responsibility and played key roles in target discovery and validation, as well as translational research programs.
David received his Ph.D. from the University of Dundee in Molecular Oncology and Biochemistry and completed a postdoctoral fellowship at Genentech.
David resides in California and enjoys outdoor activities such as skiing, snowboarding, and running.
Joseph Ferra brings to Elevation over 20 years of financial, strategic and leadership experience in the pharmaceutical/biotechnology industry. Prior to joining Elevation, he was Chief Financial Officer of Syros Pharmaceuticals where he led the development and implementation of key financial and capital strategies and contributed to corporate initiatives. Previously, he spent over a decade as an investment banker in the biotechnology and pharmaceutical industry, where he established a strong track record of advising on equity and M&A transactions. This included serving as Managing Director and Co-Head of Healthcare Investment Banking at JMP Securities and being a member of the investment banking groups at JP Morgan and UBS. Earlier in his career, Joe served in sales and engineering roles in the life science tools industry. He earned his MBA from The Stephen M. Ross School of Business at the University of Michigan. He obtained a B.S. in Chemistry with Distinction from Purdue University, where he contributed to published papers and conducted research at the National Institutes of Health.
Joe also currently serves as a member of the Executive Committee of the General Board of Directors and as the Chair of Audit & Risk Committee for the YMCA of Greater Boston.
Joe resides in Rhode Island and enjoys playing guitar, sailing, hiking and anything else involving the outdoors.
Valerie Malyvanh Jansen, MD, PhD is a physician-scientist who brings over 10 years of experience in medicine and oncology drug development. Prior to joining Elevation Oncology, Valerie was Executive Medical Director at Mersana Therapeutics, serving as the medical lead for the clinical development of antibody-drug conjugates (ADCs). Prior to that, she was Senior Medical Advisor at Eli Lilly, where she led global translational science for abemaciclib and served as the lead Clinical Research Physician on early and late phase clinical trials. Through her scientific and clinical expertise, she impacted multiple early and late stage clinical programs as well as preclinical R&D and corporate business development.
Valerie started her career in academia as a faculty member at Vanderbilt University, with a translational research program focused on understanding mechanisms of resistance to cancer targeted therapies. She also cared for patients with breast cancer in the clinic, exemplifying the bench-to-bedside model. She co-authored numerous peer-reviewed research articles and received numerous awards for her research endeavors including a Susan G. Komen Postdoctoral Fellowship, ASCO Young Investigator Award, AACR Women in Cancer Research Scholar Award, and SABCS Clinical Scholars Award.
Valerie received her MD from the University of Chicago Pritzker School of Medicine and her PhD in Molecular Sciences from the University of Tennessee Health Science Center. She completed residency in Internal Medicine and fellowship in Medical Oncology through the ABIM Physician-Scientist Research Pathway at Vanderbilt. Valerie is board certified in Internal Medicine and Medical Oncology.
Amy C. Cavers is an executive leader with more than 30 years of experience in medical affairs, clinical development and commercialization of therapeutics. Ms. Cavers was most recently Chief and SVP, Strategic Engagement and Innovation/Field Medical Team at Verastem Oncology. Prior to that she held the role of VP, Scientific Affairs at TG Therapeutics, Inc., a global biopharmaceutical company focused on the development of therapies in B-Cell malignancies for 5 years. Additional experience includes Senior Director, Scientific Strategy and Communications at Onyx Therapeutics, US Launch Lead for ixabepilone at Bristol Myers Squibb, Senior Director, Global Strategic Marketing at Millennium Pharmaceuticals and VP, Marketing at Celgene. Her experience in developing and bringing novel therapies to market includes high-profile clinical programs and launches, to include blockbuster drugs BOTOX, THALOMID, REVLIMID, VELCADE and KYPROLIS. She has developed a world-class global network and medical alliances through an innate ability to build extraordinary relationships internally and externally.
Ms. Cavers holds a Bachelor of Science degree in Animal Health Science from the University of Arizona.
Tammy Furlong is the Vice President of Finance and Accounting at Elevation Oncology, responsible for the financial oversight, management and compliance of the organization. Tammy is a solutions driven financial executive with extensive leadership experience in accounting, financial reporting, information systems, financial transformation, global strategy and management areas encompassing more than 20 years with Fortune 500 publicly traded companies. She has most recently focused on financing transactions for Biotech and Pharma companies in her role with Valkyrie Consulting. Tammy’s experience in financial transformation lends strategic focus and expertise integral for a growing portfolio.
Tammy has a BS in Accounting from Adelphi University, an MBA from Bentley University, a Graduate Certificate in Project Management from the Boston University Metropolitan College, is a Certified Public Accountant licensed in Massachusetts and a Project Management Professional with the Project Management Institute.
Tammy resides in New Hampshire and enjoys swimming, running, hiking, cycling, and skiing.
Sheila Magil, PhD is a CMC and quality expert with more than 30 years of experience working closely with both large and small biopharmaceutical companies to bring novel drugs to patients. As a Principal Consultant with BioProcess Technology Consultants, Sheila has helped many companies implement upstream and downstream manufacturing processes, quality control testing and characterization, cGMP compliance, and validation of manufacturing processes and facilities. Sheila was most recently the Managing Director for BDO USA. Sheila has a proven track record of overseeing successful internal and external development activities and preparing a wide range of regulatory filings to the FDA and EMA including 510Ks, INDs, BLAs for biologics and cell and gene therapy related materials. Sheila received her BA in Chemistry from Carnegie Mellon University and a PhD in Biochemistry from the University of Minnesota.
Sarah Ringuette has 22 years of experience in pharmaceutical development including the past 10 in regulatory affairs. Prior to Elevation, she was an Executive Director of Regulatory Affairs at Biohaven Pharmaceuticals and Head of Regulatory for the Kleo Pharmaceuticals subsidiary, Principal in ICON’s Strategic Regulatory Services consulting group and Global Regulatory Lead at Alexion and Bristol-Myers Squibb. She has led regulatory strategy for small molecules, biologics, and cell and gene therapies from pre-IND through market approval and post marketing in oncology, immunology, infectious disease, neurology, metabolic and compliment conditions and ophthalmology across rare, ultra rare and non-orphan indications. She has an MPH from Johns Hopkins University, a RAC from the Regulatory Affairs Professional Society and a BS from the George Washington University. Sarah resides in Farmington, CT where she hikes and skis with her family as much as possible and is often seen around the US at dance competitions and horse shows with her daughters.
Brian Sullivan specializes in company building, fundraising, business development and asset evaluation, corporate and product communications, branding, media engagement, and health-focused public awareness campaigns. He was a founding employee of Verastem Oncology (NASDAQ: VSTM), a biotechnology company discovering and developing oncology therapeutics. Brian was a member of Longwood Fund, a healthcare venture capital group which founds and invests in medical companies. Prior to Longwood Fund, Brian held scientific, operational and development roles within both private and public biotechnology companies and at the Massachusetts General Hospital. Brian received an M.S. in Reproductive Immunology on mechanisms of tumor development and resistance to therapy in cervical and breast cancer. Brian resides in Boston, Massachusetts and is an avid skier, ocean enthusiast, and traveler.
Siera Talbott brings over 15 years of experience in industry and government-funded projects supporting rapid growth in biologic-based therapies. Siera’s roles mostly focus on Project Management, Product Development and Corporate Development. Siera loves creating structure out of chaos, distilling technical requirements into business outcomes and leading high-functioning teams.
Siera holds a Ph.D. in Cancer Cell Biology from West Virginia University (WVU). Her academic research focused primarily on how cancer cells evolve to become chemotherapy resistant. With an extreme fascination of protein signaling networks, Siera further worked on cell survival and toxicity from nanoparticle exposure for the National Institute of Occupational Safety and Health (NIOSH). Siera went on to setup two first-in-kind Bionano laboratories for WVU serving multiple academic departments, government and industry nearby. During this time, Siera also developed the Environmental Health & Safety program used by the School of Engineering.
As Director of Project Management at Argos Therapeutics (Durham, NC), Siera managed all the operational projects for commercial launch of an autologous cell therapy product for Renal Cell Carcinoma. Later, as Head of Product Launch & Operations for a French biotech company (Erytech Pharma, Lyon, FR), Siera led the expansion into the U.S., including the construction and startup of a GMP manufacturing facility in Princeton, N.J. In conjunction with expansion efforts, she has managed Global Supply Chain and Program Management.
As a contractor, Siera provided clients with CMC and operational strategy support to drive forward early stage companies to the next clinical phase. With many favorite things, she enjoys driving efforts focused on risk and change management, scenario planning and decision analysis.
Robert C. Yang has over 10 years of experience serving as counsel to public companies during stages of substantial growth, mainly in the biotechnology industry. Prior to joining Elevation Oncology, he was Executive Director and Assistant General Counsel at REGENXBIO, a leading gene therapy company, where he advised on several major capital markets and corporate development transactions in addition to legal matters across all business functions. Earlier in his career, Robert was an associate at the international law firm of Gibson, Dunn & Crutcher, where he practiced in the areas of capital markets, securities regulation and corporate governance. He received his J.D. with honors from New York University School of Law and his B.S. in Economics from Duke University.
Board of Directors
Shawn M. Leland is the Founder and Chief Executive Officer of Elevation Oncology overseeing all day-to-day operations. Shawn brings over a decade of experience in medical affairs and business development for the pharmaceutical/biotech industry, with a focus on building collaborations to realize the full potential of targeted and personalized therapeutics. Shawn has been involved in global transactions totaling more than $450 million in upfront payments and milestone payments at Eli Lilly, ARIAD Pharmaceuticals, Argos Therapeutics and Verastem Oncology. Shawn has also served as an expert strategic consultant for Catenion providing guidance on portfolio management for pharmaceutical/biotech companies.
Shawn resides in Denver, Colorado and enjoys snowboarding, hiking and cycling.
Michael Carruthers currently serves as the Chief Financial Officer of Edgewise Therapeutics (NASDAQ: EWTX). Mr. Carruthers has over 20 years of experience serving as Chief Financial Officer for publicly-traded biopharmaceutical companies, with extensive experience across corporate finance and strategic planning including IPOs, secondary offerings and M&A transactions. Most recently, Mr. Carruthers consulted as Chief Financial Officer for several private and public companies. Previously, Mr. Carruthers served as Interim President of Nivalis Therapeutics, a publicly traded company acquired by Alpine Immune Sciences, in 2017 and Chief Financial Officer and Secretary from 2015 to 2017. From 1998 to 2015, he served as Chief Financial Officer for Array BioPharma Inc., a publicly traded company acquired by Pfizer Inc. Prior to this, he served as Chief Financial Officer of Sievers Instruments, Treasurer and Controller for the Waukesha division of Dover Corporation and Accountant with Coopers & Lybrand. Mr. Carruthers received a B.S. in accounting from the University of Colorado and a M.B.A. from the University of Chicago.
Tim Clackson, Ph.D., is President and Chief Executive Officer of Theseus Pharmaceuticals. Tim most recently served as President and Chief Technology Officer at Xilio Therapeutics, a privately held oncology company developing tumor-selective immunotherapies, where he led the development of the company’s technology and product strategy. From 1994 to 2018, Tim was with ARIAD Pharmaceuticals, where he was President of Research & Development and Chief Scientific Officer. He played a key role in the company’s evolution from early research to a global commercial oncology company, and its subsequent acquisition by Takeda. He led the multi-disciplinary R&D team that internally discovered and developed five clinical-stage product candidates, including ICLUSIG® (ponatinib), approved for patients with treatment-resistant Ph+ leukemias; ALUNBRIG® (brigatinib), approved for ALK+ non-small cell lung cancer (NSCLC); and EXKIVITY® (mobocertinib), approved for EGFR Exon20 insertion+ NSCLC. Prior to ARIAD, Tim was a postdoctoral research fellow at Genentech. He received his Ph.D. in Biology from the University of Cambridge, and his B.A. in Biochemistry from the University of Oxford. Tim serves as a director on the boards of Forma Therapeutics, Theseus Pharmaceuticals, and the Massachusetts Biotechnology Council (MassBio).
Steve Elms is a Managing Partner at Aisling Capital, a leading life sciences investment firm. Prior to joining Aisling, he was a Principal in the Life Sciences Investment Banking Group of Chase H&Q (formerly Hambrecht & Quist), where he was involved in over 60 financing and M&A transactions, helping clients raise in excess of $3.3 billion in capital. Prior to H&Q, Mr. Elms traded mortgage-backed securities at Donaldson, Lufkin & Jenrette. His previous healthcare sector experience includes over two years as a pharmaceutical sales representative for Marion Laboratories and two years as a consultant for The Wilkerson Group. Mr. Elms currently serves as a director of ADMA Biologics, Marker Therapeutics, Zosano Pharma and was previously Chairman of the Board of LOXO Oncology. He also serves on the INVO Board at Northwestern University. He received his M.B.A. from the Kellogg Graduate School of Management at Northwestern University and his B.A. in Human Biology from Stanford University.
Lori Hu is Managing Director at Vertex Ventures HC. Ms. Hu joined in 2015 to help establish the US office and manages global healthcare investments in biotech, medical devices and digital health. She manages a portfolio of over a dozen companies across two funds. Lori serves on the Board of Directors for Palleon Pharma, Blackthorn Therapeutics, Elevation Oncology and Kona Medical, and is a board observer for Ivantis and Moximed.
Before Vertex, Lori was an Associate Director for Business Development at Bristol-Myers Squibb, identifying and executing licensing and partnership transactions. She has also worked with SR One, the corporate venture capital arm of GlaxoSmithKline. Previously, she was a strategy consultant at Accenture, advising biopharmaceutical clients on strategic projects across the US and Asia.
Lori graduated with an MBA from The Wharton School, and MA in International Studies from the University of Pennsylvania where she was a Leonard Lauder Fellow. She also holds a BSE in Biomedical Engineering from Duke University. She is based in the Bay Area.
Colin Walsh, PhD is a Partner at Qiming Venture Partners USA, based in Los Altos, CA. Before joining Qiming, Dr. Walsh was a Vice President on the life science investment team at NanoDimension where he sourced, structured, and managed investments in biotech, biopharma, and platform companies. Dr. Walsh was an early employee at Precision NanoSystems (PNI), a 5AM Ventures backed biotech developing a suite of technologies to enable the development and manufacture of complex drug formulations. At PNI, he focused extensively on RNA- and DNA-based therapeutics, and held a variety of product and business development roles where he worked to define the strategy and direction of the business.
Dr. Walsh earned a Ph.D. from the UC Berkeley – UCSF Graduate Program in Bioengineering where he worked on novel delivery systems for RNA-based therapeutics as an NSF Graduate Research Fellow. He holds a Management of Technology certificate from the UC Berkeley Haas School of Business, and a dual BS with Honors in Chemical Engineering and Biochemistry from the University of Massachusetts, Amherst.
Dr. Walsh currently serves on the business advisory board for the Harvard Medical School Initiative for RNA Medicine. He is also an advisor to the Stanford SPARK program and the UCSF Catalyst program where he provides mentorship and support to student- and faculty-led translational research projects.
Scientific Advisory Committee
Dr. Siraj M. Ali is a physician-scientist and VP of clinical development at EQRx, a Cambridge area biotechnology company. Previously, he led translational research efforts at Foundation Medicine where his group focused on identifying predictive biomarkers for targeted anti-neoplastic and cancer immunotherapies, which encompasses both work with basic cancer biology and exceptional responders. Siraj has co-authored more than 200 peer-reviewed manuscripts, which have accrued nearly 20,000 citations, in journals such as The Oncologist, JCO-Precision Oncology, Cancer Discovery, Journal of Clinical Oncology (JCO), and others. He has given invited and juried presentations at international conferences. Siraj serves as a reviewer for multiple life-sciences journals and is a member of a NIH study section focused on drug development for oncology.
Siraj earned his BS in Biophysics Phi Beta Kappa from the Johns Hopkins University and an MD-PhD program from Harvard Medical School supported by HHMI fellowships and the Medical Scientist Training Program. He completed residency training at the Beth Israel Deaconess Medical Center/Harvard Medical School in Boston and is board-certified in Anatomic Pathology.
Dr. Camidge’s main clinical and research interests are thoracic malignancies and developmental therapeutics. The discoveries he and his team have made have changed the standard of care for the treatment of lung cancer multiple times. He has authored over 200 academic publications, including in the Journal of Thoracic Oncology, Lancet Oncology, and New England Journal of Medicine. He has received numerous awards including the Bonnie J. Addario International Lectureship Award and The Lung Cancer Foundation’s Breath Away From The Cure Award. In 2017, 2018 and 2019, he was internationally recognized as a highly cited researcher ranked in the top 1% of all of Clinical Medicine by Clarivate Analytics Web of Science. He is the National Medical Director of the Academic Thoracic Oncology Medical Investigators Consortium (ATOMIC), a member of the VIA Oncology Lung Cancer Pathways Committee and a past-member of the National Comprehensive Cancer Network Lung Cancer Committee.
Dr. Alexander Drilon is the Acting Chief of the Early Drug Development Service and a medical oncologist on the Thoracic Oncology Service at Memorial Sloan Kettering Cancer Center in New York. His research focuses on the development of targeted therapy for genomic subsets of lung cancer and other solid tumors, including cancers that harbor fusions involving ALK, ROS1, RET, and NTRK1/2/3, and MET exon 14 skipping alterations. He is a recipient of American Society for Clinical Oncology (ASCO)/Conquer Cancer Foundation Career Development and Young Investigator Awards, and grants from the International Association for the Study of Lung Cancer and the Lung Cancer Research Foundation. Dr. Drilon is also a member of the Editorial Board of ASCO University.
Professor Ou is board-certified in Internal Medicine (2020 renewal) and Medical Oncology (2023 renewal) by the American Board of Internal Medicine
He has published more than 180 peer-reviewed manuscripts (including New England Journal of Medicine, Lancet Oncology, Journal of Clinical Oncology, Cancer Discovery, Nature Medicine) primarily in the field in targeted therapy including resistance mechanisms to targeted therapy in lung cancer.
In particular, Professor Ou is one of the seven original principal investigators for the still ongoing phase I crizotinib trial that has led to the approval of crizotinib for the treatment of anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer (NSCLC) and ROS1-rearranged NSCLC which is now currently investigating the activity of crizotinib in MET exon 14 altered NSCLC. Other clinical research that Professor Ou has involved in has led to the approval of afatinib in uncommon EGFR mutations, Alectinib and Lorlatinib for ALK TKI-refractory ALK+ NSCLC.
Currently first-in-human phase 1 trials that Professor Ou are conducting includes a 3G ROS1/2G NTRK TKI (Repotrecitnib), a next generation RET inhibitor (BlU667), RMC-4630 (SHP2 inhibitor) as a single agent or in combination, and MRTX849 (direct covalent allosteric KRAS G12C inhibitor). The newest target Professor Ou is involved in is targeting NRG1+ fusion malignancies. Professor Ou also actively collaborate with commercial sequencing companies to mine their database to investigate their database on resistance mechanisms and treatment outcome to targeted therapy and also identification of extremely rare actionable driver mutations.
Professor Ou is the editor-in-chief of Lung Cancer: Targets and Therapy and Associate editor of Journal of Thoracic Oncology, editorial board member for Annals of Oncology, Critical Reviews in Oncology/Hematology, Clinical Lung Cancer, and Translational Lung Cancer Research. He is a member of the scientific program committee for metastatic non-small lung cancer track for the American Society of Clinical Oncology (ASCO) (2016-2018).
Dr. Kunkel holds more than two decades of experience in oncology and immunology drug development and commercialization. Dr. Kunkel currently serves on the Board of Directors of Curis, Inc., Nurix Therapeutics, ORIC Pharmaceuticals, and Maverick Therapeutics. She was previously the acting Chief Medical Officer at Loxo Oncology and subsequently served on their board. She also served as Chief Medical Officer at Pharmacyclics (acquired by AbbVie) and Proteolix, Inc. (acquired by Onyx Pharmaceuticals), where she contributed to the global approvals of cancer therapeutics IMBRUVICA® and Kyprolis®, respectively. She participates as a scientific advisor to multiple clients including Atreca, Jasper Therapeutics, Oncopeptides, Oryzon, Rain Therapeutics, and Enliven Therapeutics. Dr. Kunkel spent ten years in academic medicine and served as a faculty member at the Bone Marrow Transplant Unit in the Division of Hematology/Oncology at University of California, Los Angeles. She is board certified in internal medicine and held board certifications in hematology and oncology and holds a B.A. in biology from the University of California, San Diego.